GSK3368715 (trihydrochloride), CAS [[2227587-26-8]] Preis auf Anfrage
Artikelnummer:
MCE-HY-128717B
| Artikelname: |
GSK3368715 (trihydrochloride), CAS [[2227587-26-8]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-128717B |
| Hersteller Artikelnummer: |
HY-128717B |
| Alternativnummer: |
MCE-HY-128717B-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| Alternative Synonym: |
EPZ019997 (trihydrochloride) |
| GSK3368715 trihydrochloride (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 trihydrochloride (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity[1]. |
| Molekulargewicht: |
475.92 |
| CAS Nummer: |
[2227587-26-8] |
| Formel: |
C20H41Cl3N4O2 |
| Target-Kategorie: |
Histone Methyltransferase |
| Anwendungsbeschreibung: |
MCE Product type: Reference compound |
