WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX[1].
Molekulargewicht:
593.71
Reinheit:
99.46
CAS Nummer:
[2595314-46-6]
Formel:
C34H27NO5S2
Target-Kategorie:
Apoptosis,VDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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