Pulrodemstat (CC-90011) is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC50 of 0.25 nM. Pulrodemstat is less enzymatic inhibition against LSD2, MAO-A, and MAO-B. Pulrodemstat induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity[1].
Molekulargewicht:
451.47
Reinheit:
98.86
CAS Nummer:
[1821307-10-1]
Formel:
C24H23F2N5O2
Target-Kategorie:
Histone Demethylase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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