Benzyl-alpha-GalNAc is a potent O-glycosylation inhibitor. Benzyl-alpha-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-alpha-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation[1][2][3].
Molekulargewicht:
311.33
Reinheit:
99.93
CAS Nummer:
[3554-93-6]
Formel:
C15H21NO6
Target-Kategorie:
Glycosyltransferase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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