BI-4020, CAS [[2664214-60-0]]

Produktübersicht

• Artikelname: BI-4020, CAS [[2664214-60-0]]
• Artikelnummer: MCE-HY-129550
• Hersteller Artikelnummer: HY-129550
• Alternativnummer: MCE-HY-129550-1MG,MCE-HY-129550-10MG,MCE-HY-129550-25MG,MCE-HY-129550-50MG,MCE-HY-129550-100MG,MCE-HY-129550-10MMX1ML,MCE-HY-129550-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BI-4020 is a fourth-generation, orally active, and non-covalent EGFR tyrosine kinase inhibitor. BI-4020 inhibits not only the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines) but also the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM). BI-4020 also shows activity against EGFR wt (IC50=190 nM). BI-4020 shows high kinome selectivity and good DMPK properties[1].

Produkteigenschaften

• Molekulargewicht: 542.68
• Reinheit: 99.30
• CAS Nummer: [2664214-60-0]
• Formel: C30H38N8O2
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound