Quizartinib, CAS [[950769-58-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: Quizartinib, CAS [[950769-58-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-13001
• Hersteller Artikelnummer: HY-13001
• Alternativnummer: MCE-HY-13001-10MMX1ML,MCE-HY-13001-1MG,MCE-HY-13001-200MG,MCE-HY-13001-500MG,MCE-HY-13001-50MG,MCE-HY-13001-10MG,MCE-HY-13001-5MG,MCE-HY-13001-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: AC220, AC708

Produktbeschreibung

Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis[1].

Produkteigenschaften

• Molekulargewicht: 560.67
• Reinheit: 99.08
• CAS Nummer: [950769-58-1]
• Formel: C29H32N6O4S
• Target-Kategorie: Apoptosis,FLT3,Ligands for Target Protein for PROTAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound