DM3-SMe is a maytansine derivative and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs), which can be linked to antibody through disulfide bond or stable thioether bond. DM3-SMe shows highly cytotoxic activity in vitro with an IC50 of 0.0011 nM[1][2].
Molekulargewicht:
812.43
CAS Nummer:
[796073-70-6]
Formel:
C38H54ClN3O10S2
Target-Kategorie:
ADC Payload,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: ADC Related
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