Azido-PEG9-amine is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG9-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molekulargewicht:
482.57
Reinheit:
98
CAS Nummer:
[1207714-69-9]
Formel:
C20H42N4O9
Target-Kategorie:
ADC Linker,PROTAC Linkers
Anwendungsbeschreibung:
MCE Product type: ADC Related
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