LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
Molekulargewicht:
254.24
Reinheit:
98.12
CAS Nummer:
[7758-73-8]
Formel:
C15H10O4
Target-Kategorie:
Atg8/LC3,Autophagy
Anwendungsbeschreibung:
MCE Product type: Natural Products
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