Propargyl-PEG4-acid, CAS [[1415800-32-6]]

Produktübersicht

• Artikelname: Propargyl-PEG4-acid, CAS [[1415800-32-6]]
• Artikelnummer: MCE-HY-130481
• Hersteller Artikelnummer: HY-130481
• Alternativnummer: MCE-HY-130481-500MG,MCE-HY-130481-1G,MCE-HY-130481-5G,MCE-HY-130481-25G,MCE-HY-130481-10G
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib (HY-10997)-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1]. Propargyl-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Produkteigenschaften

• Molekulargewicht: 260.28
• Reinheit: 97
• CAS Nummer: [1415800-32-6]
• Formel: C12H20O6
• Target-Kategorie: PROTAC Linkers

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound