N-piperidine Ibrutinib (hydrochloride), CAS [[2231747-18-3]]

Produktübersicht

• Artikelname: N-piperidine Ibrutinib (hydrochloride), CAS [[2231747-18-3]]
• Artikelnummer: MCE-HY-130983
• Hersteller Artikelnummer: HY-130983
• Alternativnummer: MCE-HY-130983-10MMX1ML,MCE-HY-130983-25MG,MCE-HY-130983-100MG,MCE-HY-130983-10MG,MCE-HY-130983-5MG,MCE-HY-130983-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

N-piperidine Ibrutinib hydrochloride (Compound 1) is a reversible Ibrutinib derivative. N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor with IC50s of 51.0 and 30.7 nM for WT BTK and C481S BTK, respectively[1]. N-piperidine Ibrutinib hydrochloride can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM[2].

Produkteigenschaften

• Molekulargewicht: 422.91
• Reinheit: 98.06
• CAS Nummer: [2231747-18-3]
• Formel: C22H23ClN6O
• Target-Kategorie: Btk,Ligands for Target Protein for PROTAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound