Triciferol functions as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC50=87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation. Antiproliferative and cytotoxic activities[1].
Molekulargewicht:
429.59
Reinheit:
98.61
CAS Nummer:
[957214-00-5]
Formel:
C26H39NO4
Target-Kategorie:
HDAC,VD/VDR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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