Belnacasan (Standard) is the analytical standard of Belnacasan. This product is intended for research and analytical applications. Belnacasan (VX-765) is an orally bioactive proagent of VRT-043198, which is a potent and selective inhibitor of IL-converting enzyme (ICE)/caspase-1 with Kis of 0.8 nM and less than 0.6 nM for caspase-1 and caspase-4, respectively. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1beta and IL-18 by human PBMCs with an IC50 of ~0.7 µM[1][2].
Molekulargewicht:
509.00
Reinheit:
99.97
CAS Nummer:
[273404-37-8]
Formel:
C24H33ClN4O6
Target-Kategorie:
Caspase,Reference Standards
Anwendungsbeschreibung:
MCE Product type: Reference Standards
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
