ONX-0914 (TFA)

Produktübersicht

• Artikelname: ONX-0914 (TFA)
• Artikelnummer: MCE-HY-13207A
• Hersteller Artikelnummer: HY-13207A
• Alternativnummer: MCE-HY-13207A-10MG,MCE-HY-13207A-5MG,MCE-HY-13207A-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PR-957 (TFA)

Produktbeschreibung

ONX-0914 (PR-957) TFA is a selective inhibitor of low-molecular mass polypeptide-7 (LMP7), the chymotrypsin-like subunit of the immunoproteasome. ONX-0914 TFA blocks cytokine production and attenuates progression of experimental arthritis. ONX-0914 TFA is a noncompetitive irreversible inhibitor of the mycobacterial proteasome (Ki=5.2 µM). ONX-0914 TFA reactivates latent HIV-1 through p-TEFb activation mediated by HSF-1[1][2][3].

Produkteigenschaften

• Molekulargewicht: 694.70
• Reinheit: 98.01
• Formel: C33H41F3N4O9
• Target-Kategorie: Bacterial,HIV,Proteasome

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound