PD-1/PD-L1-IN-9 hydrochloride is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 hydrochloride can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 hydrochloride also exhibits significant in vivo antitumor activity in a CT26 mouse model[1].
Molekulargewicht:
384.90
Reinheit:
98.59
Formel:
C22H25ClN2O2
Target-Kategorie:
PD-1/PD-L1
Anwendungsbeschreibung:
MCE Product type: Reference compound
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