Rivanicline (RJR-2403) hydrochloride is a neuronal nicotinic receptor agonist. Rivanicline hydrochloride is highly selective for the rat brain cortex nAChRs (Ki = 26 nM, EC50 of 732 nM) and alpha4beta2 subtype (Ki = 26 nM, EC50 = 16 µM). Rivanicline hydrochloride can significantly restore the learning impairment and cognitive dysfunction. Rivanicline hydrochloride can be used for the study of neurodegenerative diseases (such as schizophrenia or Alzheimers disease)[1][2][3][4][5].
Molekulargewicht:
198.69
Formel:
C10H15ClN2
Target-Kategorie:
nAChR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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