Dolutegravir, CAS [[1051375-16-6]]

Produktübersicht

• Artikelname: Dolutegravir, CAS [[1051375-16-6]]
• Artikelnummer: MCE-HY-13238
• Hersteller Artikelnummer: HY-13238
• Alternativnummer: MCE-HY-13238-10MMX1ML,MCE-HY-13238-500MG,MCE-HY-13238-25MG,MCE-HY-13238-100MG,MCE-HY-13238-2MG,MCE-HY-13238-5MG,MCE-HY-13238-50MG,MCE-HY-13238-1G,MCE-HY-13238-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: S/GSK1349572

Produktbeschreibung

Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].

Produkteigenschaften

• Molekulargewicht: 419.38
• Reinheit: 99.85
• CAS Nummer: [1051375-16-6]
• Formel: C20H19F2N3O5
• Target-Kategorie: HIV,HIV Integrase

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound