Selnoflast (RO7486967), formerly somalix/RG6418/IZD334, is an orally active, potent, selective and reversible small molecule NLRP3 inflammasome inhibitor. Selnoflast is a potent inhibitor of IL-1beta release stimulated by NLRP3 activation in human Alzheimers disease (AD) monocyte-derived macrophages. Selnoflast is promising for research of AD and systemic inflammatory diseases, such as ulcerative colitis and chronic obstructive pulmonary disease[1][2][3].
Molekulargewicht:
391.53
Reinheit:
99.46
CAS Nummer:
[2260969-36-4]
Formel:
C20H29N3O3S
Target-Kategorie:
Interleukin Related,NOD-like Receptor (NLR)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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