Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3, Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). IC50 value: Target: vitamin D receptor Calcitriol(1,25-Dihydroxyvitamin D3, Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3, Rocaltrol )exhibits antitumor activity, Calcitriol(1,25-Dihydroxyvitamin D3, Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
Molekulargewicht:
416.64
Reinheit:
98.04
CAS Nummer:
[66791-71-7]
Formel:
C27H44O3
Target-Kategorie:
VD/VDR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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