Thioetheramide-PC, CAS [[116457-99-9]]

Artikelnummer: MCE-HY-133233
Artikelname: Thioetheramide-PC, CAS [[116457-99-9]]
Artikelnummer: MCE-HY-133233
Hersteller Artikelnummer: HY-133233
Alternativnummer: MCE-HY-133233-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine
Thioetheramide-PC (1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine) is a structurally modified phospholipid that acts as a competitive, reversible inhibitor of secretory phospholipase A2 (sPLA2). Thioetheramide-PC has an IC50 value of 2 µM at a substrate concentration of 0.5 mM. In addition to binding to the catalytic site of sPLA2, Thioetheramide-PC also binds to the activation site of the enzyme. Thioetheramide-PC binds more tightly to the activation site than to the catalytic site. As a result of this dual interaction, at low concentrations, Thioetheramide-PC may activate phospholipase activity rather than inhibit it.
Molekulargewicht: 735.14
Reinheit: 98
CAS Nummer: [116457-99-9]
Formel: C40H83N2O5PS
Target-Kategorie: Endogenous Metabolite,Phospholipase
Anwendungsbeschreibung: MCE Product type: Reference compound