Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus, which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-kappaB. Emodic acid can also inhibit the phosphorylation of p38, ERK and JNK, the secretion of tumor-promoting cytokines IL-1beta and IL-6, and the expression of VEGF and MMP, thereby inhibiting the invasion and migration potential of cancer cells[1].
Molekulargewicht:
300.22
CAS Nummer:
[478-45-5]
Formel:
C15H8O7
Target-Kategorie:
ERK,JNK,MMP,NF-kappaB,p38 MAPK,VEGFR
Anwendungsbeschreibung:
MCE Product type: Natural Products
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