Capmatinib, CAS [[1029712-80-8]]

Produktübersicht

• Artikelname: Capmatinib, CAS [[1029712-80-8]]
• Artikelnummer: MCE-HY-13404
• Hersteller Artikelnummer: HY-13404
• Alternativnummer: MCE-HY-13404-50MG,MCE-HY-13404-500MG,MCE-HY-13404-5MG,MCE-HY-13404-10MG,MCE-HY-13404-25MG,MCE-HY-13404-200MG,MCE-HY-13404-10MMX1ML,MCE-HY-13404-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: INC280, INCB28060

Produktbeschreibung

Capmatinib (INC280, INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor (IC50=0.13 nM). Capmatinib can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib is largely metabolized by CYP3A4 and aldehyde oxidase[1][2][3].

Produkteigenschaften

• Molekulargewicht: 412.42
• Reinheit: 99.82
• CAS Nummer: [1029712-80-8]
• Formel: C23H17FN6O
• Target-Kategorie: Apoptosis,c-Met/HGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound