8-Br-dGTP (8-Bromo-dGTP) sodium (Compound 5), an 8-brominated purine nucleotide, is a syn-oriented analog of dGTP. 8-Br-dGTP sodium can be hydrolyzed by the enzyme hMTH1 protein (HY-P74740). 8-Br-dGTP sodium inhibits dGTP-activated ADP reduction with a Ki of 56 µM. 8-Br-dGTP sodium has no significant genotoxicity and mutagenic potentials during DNA synthesis[1][2][3].
Molekulargewicht:
674.00
Formel:
C10H11BrN5Na4O13P3
Target-Kategorie:
Nucleoside Antimetabolite/Analog
Anwendungsbeschreibung:
MCE Product type: Reference compound
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