alpha,beta-Methylene-ATP (dilithium), CAS [[104809-20-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-134440
Hersteller Artikelnummer:
HY-134440
Alternativnummer:
MCE-HY-134440-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
alpha,beta-Methylene-ATP dilithium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. alpha,beta-Methylene-ATP dilithium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC), this effect can be blocked by the P2X antagonist PPADS (HY-108960). alpha,beta-Methylene-ATP dilithium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects, this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). alpha,beta-Methylene-ATP dilithium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system[1][2][3].
Molekulargewicht:
519.09
CAS Nummer:
[104809-20-3]
Formel:
C11H18Li2N5O12P3
Target-Kategorie:
P2X Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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