BAY 11-7082, CAS [[19542-67-7]]

Produktübersicht

• Artikelname: BAY 11-7082, CAS [[19542-67-7]]
• Artikelnummer: MCE-HY-13453
• Hersteller Artikelnummer: HY-13453
• Alternativnummer: MCE-HY-13453-100MG,MCE-HY-13453-50MG,MCE-HY-13453-10MMX1ML,MCE-HY-13453-10MG,MCE-HY-13453-25MG,MCE-HY-13453-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: BAY 11-7821

Produktbeschreibung

BAY 11-7082 is an IkappaBalpha phosphorylation and NF-kappaB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-alpha-induced phosphorylation of IkappaB-alpha, and decreases NF-kappaB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 µM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1beta secretion in human and mouse cells[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 207.25
• Reinheit: 99.98
• CAS Nummer: [19542-67-7]
• Formel: C10H9NO2S
• Target-Kategorie: Apoptosis,Autophagy,Deubiquitinase,IKK,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound