KW-2478, CAS [[819812-04-9]]

Produktübersicht

• Artikelname: KW-2478, CAS [[819812-04-9]]
• Artikelnummer: MCE-HY-13468
• Hersteller Artikelnummer: HY-13468
• Alternativnummer: MCE-HY-13468-5MG,MCE-HY-13468-10MMX1ML,MCE-HY-13468-100MG,MCE-HY-13468-50MG,MCE-HY-13468-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KW-2478 is an HSP90 inhibitor (IC50 = 3.8 nM). KW-2478 inhibits the growth and induces apoptosis in chronic myeloid leukemia (CML) cells and liver cancer cells. KW-2478 weakens the BCR/ABL and MAPK signaling pathways, leading to increased p27 and p21 expression and decreased cyclin B1 expression. KW-2478 downregulates STAT3 expression. KW-2478 may be used in research on cancers such as CML and liver cancer[1][2].

Produkteigenschaften

• Molekulargewicht: 574.66
• Reinheit: 99.53
• CAS Nummer: [819812-04-9]
• Formel: C30H42N2O9
• Target-Kategorie: Apoptosis,Bcr-Abl,CDK,HSP,p38 MAPK,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound