YM-341619 (AS1617612) is a potent and orally active STAT6 inhibitor with an IC50 of 0.70 nM. YM-341619 inhibits Th2 differentiation in mouse spleen T cells induced by IL-4 (IC50=0.28 nM) without affecting Th1 cell differentiation[1]. YM-341619 is a promising compound for the the research of allergic diseases, such as allergic asthma[2].
Molekulargewicht:
458.44
Reinheit:
98.01
CAS Nummer:
[643082-52-4]
Formel:
C22H21F3N6O2
Target-Kategorie:
STAT
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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