4-Oxo Docosahexaenoic Acid, CAS [[845673-74-7]] Preis auf Anfrage
Artikelnummer:
MCE-HY-134997
Hersteller Artikelnummer:
HY-134997
Alternativnummer:
MCE-HY-134997-250UG,MCE-HY-134997-100UG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
4-oxo DHA
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of Docosahexaenoic acid (HY-B2167) with antiproliferative and PPARgamma agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 µM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARgamma and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 µM.
Molekulargewicht:
342.47
CAS Nummer:
[845673-74-7]
Formel:
C22H30O3
Target-Kategorie:
PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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