Mitoxantrone (diacetate), CAS [[70711-41-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-13502B
Hersteller Artikelnummer:
HY-13502B
Alternativnummer:
MCE-HY-13502B-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
Mitozantrone (diacetate), NSC 301739 (diacetate)
Mitoxantrone diacetate is a potent topoisomerase II inhibitor. Mitoxantrone diacetate also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 µM. Mitoxantrone diacetate induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone diacetate shows antitumor activity[1][2][3][4]. Mitoxantrone diacetate also has anti-orthopoxvirus activity with EC50s of 0.25 µM and and 0.8 µM for cowpox and monkeypox, respectively[5].
