Emavusertib (phosphate), CAS [[2376399-38-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Emavusertib (phosphate), CAS [[2376399-38-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-135317F
• Hersteller Artikelnummer: HY-135317F
• Alternativnummer: MCE-HY-135317F-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CA-4948 (phosphate)

Produktbeschreibung

Emavusertib phosphate (CA-4948 phosphate) is the phosphate salt form of Emavusertib (HY-135317). Emavusertib phosphate is an orally active inhibitor for IRAK4 (IC50=57 nM) and FLT3. Emavusertib phosphate inhibits NF-kappaB and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib phosphate exhibits antitumor activity in mouse model[1][2][3].

Produkteigenschaften

• Molekulargewicht: 589.49
• CAS Nummer: [2376399-38-9]
• Formel: C24H28N7O9P
• Target-Kategorie: Apoptosis,FLT3,IRAK,MyD88,NF-kappaB

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound