N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3].
Molekulargewicht:
463.41
Reinheit:
99.68
CAS Nummer:
[1332391-11-3]
Formel:
C20H13F4N5O2S
Target-Kategorie:
Androgen Receptor,Cytochrome P450
Anwendungsbeschreibung:
MCE Product type: Reference compound
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