RK-682 (hemicalcium), CAS [[332131-32-5]] Preis auf Anfrage
Artikelnummer:
MCE-HY-135564
Hersteller Artikelnummer:
HY-135564
Alternativnummer:
MCE-HY-135564-500UG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
RK-682 hemicalcium is the hemicalcium salt form of RK-682 (HY-135564A). RK-682 hemicalcium is the inhibitor for protein tyrosine phosphatase (PTPase), heparanase, phospholipase A2 and HIV-1 protease. RK-682 hemicalcium inhibits the dephosphorylation of CD45 (IC50 is 54 µM) and VHR (IC50 is 2.0 µM), and thereby inhibits the ERK signaling pathway. RK-682 hemicalcium inhibits the cell viability of cancer cell MGH-U3, T24 and UROtsa with IC50s of 78.2, 43.2 and 145 nM, respectively, arrests the cell cycle at G1/S phase, inhibits the cell migration and autophagy in MGH-U3 and T24[1][2][3].
