11-Ketodihydrotestosterone (11-KDHT, 5alpha-Dihydro-11-keto testosterone) is an endogenous steroid and a metabolite of 11beta-Hydroxyandrostenedione. 11-Ketodihydrotestosterone is an active androgen and is also a potent androgen receptor (AR) agonist with a Ki of 20.4 nM and an EC50 of 1.35 nM for human AR. 11-Ketodihydrotestosterone drives gene regulation, protein expression and cell growth in androgen-dependent prostate cancer cells[1][2].
Molekulargewicht:
304.42
Reinheit:
99.87
CAS Nummer:
[32694-37-4]
Formel:
C19H28O3
Target-Kategorie:
Androgen Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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