ZX-29, CAS [[2254805-62-2]]

Produktübersicht

• Artikelname: ZX-29, CAS [[2254805-62-2]]
• Artikelnummer: MCE-HY-135887
• Hersteller Artikelnummer: HY-135887
• Alternativnummer: MCE-HY-135887-1MG,MCE-HY-135887-5MG,MCE-HY-135887-50MG,MCE-HY-135887-100MG,MCE-HY-135887-10MMX1ML,MCE-HY-135887-10MG,MCE-HY-135887-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

ZX-29 is a potent and selective ALK inhibitor with an IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX-29 is inactive against EGFR. ZX-29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX-29 also induces protective autophagy and has antitumor effect[1].

Produkteigenschaften

• Molekulargewicht: 518.03
• Reinheit: 98.59
• CAS Nummer: [2254805-62-2]
• Formel: C23H28ClN7O3S
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Apoptosis,Autophagy

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1