Synucleozid hydrochloride (NSC 377363 hydrochloride) is a potent inhibitor of the SNCA mRNA that encodes alpha-synuclein protein. Synucleozid selectively targets the alpha-synuclein mRNA 5' UTR at the designed IRE site, decreases the amount of SNCA mRNA loaded into polysomes and thereby inhibits SNCA translation. Synucleozid has the potential for the investigation of Parkinsons disease[1].
Molekulargewicht:
404.90
Reinheit:
98.23
CAS Nummer:
[2741856-68-6]
Formel:
C22H21ClN6
Target-Kategorie:
DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
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