BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader (PROTAC), with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity[1].
Molekulargewicht:
832.90
Reinheit:
99.76
CAS Nummer:
[2349356-09-6]
Formel:
C43H48N10O8
Target-Kategorie:
CDK,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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