BC-LI-0186, CAS [[695207-56-8]]

Produktübersicht

• Artikelname: BC-LI-0186, CAS [[695207-56-8]]
• Artikelnummer: MCE-HY-136265
• Hersteller Artikelnummer: HY-136265
• Alternativnummer: MCE-HY-136265-10MMX1ML,MCE-HY-136265-5MG,MCE-HY-136265-10MG,MCE-HY-136265-25MG,MCE-HY-136265-100MG,MCE-HY-136265-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase (LRS, LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (IC50=46.11 nM). BC-LI-0186 competitively binds to the RagD interacting site of LRS (Kd=42.1 nM) and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated MTOR mutants and the growth of rapamycin-resistant cancer cells. BC-LI-0186 is a promising agent for lung cancer research[1][2].

Produkteigenschaften

• Molekulargewicht: 429.53
• Reinheit: 99.20
• CAS Nummer: [695207-56-8]
• Formel: C22H27N3O4S
• Target-Kategorie: Aminoacyl-tRNA Synthetase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1