4-hydroxy Nonenal Mercapturic Acid, CAS [[146764-24-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: 4-hydroxy Nonenal Mercapturic Acid, CAS [[146764-24-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-136410
• Hersteller Artikelnummer: HY-136410
• Alternativnummer: MCE-HY-136410-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common omega-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.

Produkteigenschaften

• Molekulargewicht: 319.42
• CAS Nummer: [146764-24-1]
• Formel: C14H25NO5S
• Target-Kategorie: Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products