MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 µM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6[1][2].
Molekulargewicht:
439.94
CAS Nummer:
[491611-55-3]
Formel:
C20H30ClN5O4
Target-Kategorie:
P2Y Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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