S2116, CAS [[2262489-89-2]]

Produktübersicht

• Artikelname: S2116, CAS [[2262489-89-2]]
• Artikelnummer: MCE-HY-136522
• Hersteller Artikelnummer: HY-136522
• Alternativnummer: MCE-HY-136522-10MG,MCE-HY-136522-100MG,MCE-HY-136522-25MG,MCE-HY-136522-10MMX1ML,MCE-HY-136522-50MG,MCE-HY-136522-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice[1].

Produkteigenschaften

• Molekulargewicht: 437.91
• Reinheit: 98.05
• CAS Nummer: [2262489-89-2]
• Formel: C22H26ClF2N3O2
• Target-Kategorie: Apoptosis,Histone Demethylase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound