7-Hydroxystaurosporine (UCN-01), a derivative of Staurosporine (HY-15141), is a selective protein kinase C (PKC) inhibitor with antitumor activity. 7-hydroxystaurosporine induces apoptosis and inhibits cell proliferation in colon carcinoma and leukemia cells, suppresses invasion and migration in glioblastoma cells. 7-Hydroxystaurosporine exhibits efficacy in breast cancer xenograft mouse models. 7-Hydroxystaurosporine can be used for colon carcinoma, breast cancer, glioblastoma and leukemia research[1][2][3].
Molekulargewicht:
482.53
Reinheit:
97.5
CAS Nummer:
[112953-11-4]
Formel:
C28H26N4O4
Target-Kategorie:
Apoptosis,Cadherin,CDK,PKC
Anwendungsbeschreibung:
MCE Product type: Reference compound
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