Ro 04-5595 is a selective antagonist with specific activity against the NR2B subunit of the NMDA receptor. Ro 04-5595 exhibits favorable pharmacokinetic properties in in vitro and in vivo studies, with rapid uptake and clearance. Ro 04-5595 exhibits strong binding in NR2B receptor-enriched regions and low binding in the cerebellum. Ro 04-5595 is able to effectively inhibit specific binding, showing high affinity for the NR2B receptor and a clear ranking of binding affinity with a variety of other compounds[1].
Molekulargewicht:
331.84
CAS Nummer:
[194089-07-1]
Formel:
C19H22ClNO2
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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