Vodobatinib (K0706) is a potent, third generation and orally active Bcr-Abl1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I. Vodobatinib can be used for chronic myeloid leukemia (CML) research[1][2]. Vodobatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molekulargewicht:
453.92
Reinheit:
98.09
CAS Nummer:
[1388803-90-4]
Formel:
C27H20ClN3O2
Target-Kategorie:
Bcr-Abl
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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