OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1,IC50=23 nM). OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research[1].
Molekulargewicht:
390.91
Reinheit:
99.94
CAS Nummer:
[2088453-21-6]
Formel:
C19H27ClN6O
Target-Kategorie:
Others
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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