4-Methylumbelliferyl-alpha-D-Glucopyranoside (4-Methylumbelliferyl-alpha-D-Glucose) is a fluorescent substrate for alpha-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. The emission wavelength of 4-Methylumbelliferyl-alpha-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. 4-Methylumbelliferyl-alpha-D-Glucopyranoside can be used as a biomarker for Fabry and Pompe diseases to quantify alpha-glucosidase activity in infant blood spot samples.
Molekulargewicht:
338.31
Reinheit:
99.99
CAS Nummer:
[17833-43-1]
Formel:
C16H18O8
Target-Kategorie:
Fluorescent Dye,Glycosidase
Anwendungsbeschreibung:
MCE Product type: Dye Reagents
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