Tazemetostat, CAS [[1403254-99-8]]

Produktübersicht

• Artikelname: Tazemetostat, CAS [[1403254-99-8]]
• Artikelnummer: MCE-HY-13803
• Hersteller Artikelnummer: HY-13803
• Alternativnummer: MCE-HY-13803-500MG,MCE-HY-13803-1MG,MCE-HY-13803-10MG,MCE-HY-13803-1G,MCE-HY-13803-100MG,MCE-HY-13803-50MG,MCE-HY-13803-10MMX1ML,MCE-HY-13803-200MG,MCE-HY-13803-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: EPZ-6438, E-7438

Produktbeschreibung

Tazemetostat (EPZ-6438) is a potent, selective and orally available EZH2 inhibitor. Tazemetostat inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 with a Ki value of 2.5 nM. Tazemetostat inhibits EZH2 with IC50s of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat inhibits rat EZH2 with an IC50 of 4 nM. Tazemetostat also inhibits EZH1 with an IC50 of 392 nM. Tazemetostat induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells[1].

Produkteigenschaften

• Molekulargewicht: 572.74
• Reinheit: 99.93
• CAS Nummer: [1403254-99-8]
• Formel: C34H44N4O4
• Target-Kategorie: Apoptosis,Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound