Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity[1][2][3][4][5].
Molekulargewicht:
554.72
Reinheit:
99.60
CAS Nummer:
[134381-21-8]
Formel:
C28H50N4O7
Target-Kategorie:
Apoptosis,Proteasome
Anwendungsbeschreibung:
MCE Product type: Natural Products
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