GNE-987 GSH linker-2

Produktübersicht

• Artikelname: GNE-987 GSH linker-2
• Artikelnummer: MCE-HY-138634
• Hersteller Artikelnummer: HY-138634
• Alternativnummer: MCE-HY-138634-1MG,MCE-HY-138634-25MG,MCE-HY-138634-10MG,MCE-HY-138634-5MG,MCE-HY-138634-50MG,MCE-HY-138634-100MG,MCE-HY-138634-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GNE-987 GSH linker-2 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. GNE-987 GSH linker-2 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.23 nM and 0.38 nM, respectively[1].

Produkteigenschaften

• Molekulargewicht: 1292.56
• Reinheit: 99.48
• Formel: C61H75F2N9O12S4
• Target-Kategorie: Epigenetic Reader Domain,PROTAC-Linker Conjugates for PAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: ADC Related