Ro 31-8220 (mesylate) (Standard), CAS [[138489-18-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: Ro 31-8220 (mesylate) (Standard), CAS [[138489-18-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-13866R
• Hersteller Artikelnummer: HY-13866R
• Alternativnummer: MCE-HY-13866R-50MG,MCE-HY-13866R-25MG,MCE-HY-13866R-10MG,MCE-HY-13866R-100MG,MCE-HY-13866R-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Ro 31-8220 mesylate (Standard) is the analytical standard of Ro 31-8220 mesylate (HY-13866). This product is intended for research and analytical applications. Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCalpha, PKCbetaI, PKCbetaII, PKCgamma, PKCepsilon and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3beta (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. Ro 31-8220 mesylate can also inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, and these effects possess pharmacological properties independent of PKC[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 553.65
• CAS Nummer: [138489-18-6]
• Formel: C26H27N5O5S2
• Target-Kategorie: JNK,PKC,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards