N-Desethyl Sunitinib (hydrochloride) (Standard) Preis auf Anfrage

Artikelnummer: MCE-HY-138813R
Artikelname: N-Desethyl Sunitinib (hydrochloride) (Standard) Preis auf Anfrage
Artikelnummer: MCE-HY-138813R
Hersteller Artikelnummer: HY-138813R
Alternativnummer: MCE-HY-138813R-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: SU-12662 (hydrochloride) (Standard)
Glycochenodeoxycholic acid sodium salt (Standard) is the analytical standard of Glycochenodeoxycholic acid sodium salt. This product is intended for research and analytical applications. Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC)[1][2][3][4].
Molekulargewicht: 406.88
Formel: C20H24ClFN4O2
Target-Kategorie: Drug Metabolite,Reference Standards
Anwendungsbeschreibung: MCE Product type: Reference Standards